Reno-renal syndrome: cross-talk between kidneys.

254 Iranian Journal of Kidney Diseases | Volume 3 | Number 4 | October 2009 addition, the pathological process in the affected pediatric cases is owing to the acute obstruction from melamine crystal that is unlikely to cause proteinuria. Therefore, the rational for screening for proteinuria in pediatric cases exposed to melamine is not supported. Some limitations of this work should be noted. First, this is a bioinformatics study that still requires further in vitro and in vivo confirmation. Second, there are some new information on uric acid crystallized melamine in urine, but it is not observed in all cases and is not studied in this work due to lack of basic information on its structure.